Product Data Sheet
NR2F1 agonist 1
Catalog No. A85359
NR2F1 agonist 1 is a selective agonist of the nuclear receptor NR2F1, designed to activate dormancy programs in malignant cells. This compound up-regulates NR2F1 and its downstream target genes, leading to neural crest-like differentiation and growth suppression in head and neck squamous cell carcinoma (HNSCC). Additionally, NR2F1 agonist 1 has demonstrated the ability to inhibit tumor growth in preclinical mouse models, making it a valuable tool for research into cancer dormancy and therapeutic strategies.
Chemical Information
| Catalog Num | A85359 |
|---|---|
| M. Wt | 470.63 |
| Formula | C28H30N4OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 374101-64-1 |
| Synonyms | |
| SMILES | O=C1C2=C(N3C(SCC)=NN=C3N1CCC4=CC=CC=C4)C5=C(CC26CCCCC6)C=CC=C5 |
Biological Activity
| Description | NR2F1 agonist 1 is a selective agonist of the nuclear receptor NR2F1, designed to activate dormancy programs in malignant cells. This compound up-regulates NR2F1 and its downstream target genes, leading to neural crest-like differentiation and growth suppression in head and neck squamous cell carcinoma (HNSCC). Additionally, NR2F1 agonist 1 has demonstrated the ability to inhibit tumor growth in preclinical mouse models, making it a valuable tool for research into cancer dormancy and therapeutic strategies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
