Product Data Sheet
CPAG-1
Catalog No. A85405
CPAG-1 is a small-molecule activator of the progesterone receptor membrane component 2 (PGRMC2). It enhances mitochondrial heme delivery to the nucleus, promoting the activation of genes associated with thermogenesis in brown adipose tissue, such as Ucp1 and Pgc-1α, while also decreasing lipid accumulation. Additionally, CPAG-1 has demonstrated the potential to lower fasting blood sugar and insulin levels, and improve glucose tolerance and insulin sensitivity. This compound is valuable for researching the mechanisms underlying type 2 diabetes.
Chemical Information
| Catalog Num | A85405 |
|---|---|
| M. Wt | 326.43 |
| Formula | C20H26N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2094991-62-3 |
| Synonyms | |
| SMILES | CC(C[C@@H](C(NC1=CC=C2C=CC=CC2=C1)=O)NC(CCC)=O)C |
Biological Activity
| Description | CPAG-1 is a small-molecule activator of the progesterone receptor membrane component 2 (PGRMC2). It enhances mitochondrial heme delivery to the nucleus, promoting the activation of genes associated with thermogenesis in brown adipose tissue, such as Ucp1 and Pgc-1α, while also decreasing lipid accumulation. Additionally, CPAG-1 has demonstrated the potential to lower fasting blood sugar and insulin levels, and improve glucose tolerance and insulin sensitivity. This compound is valuable for researching the mechanisms underlying type 2 diabetes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
