Product Data Sheet
Debutyldronedarone hydrochloride
Catalog No. A85446
Debutyldronedarone hydrochloride is a selective inhibitor of the thyroid hormone receptor α1 (TRα1), derived from the main metabolite of Dronedarone. This compound effectively inhibits T3 binding to TRα1 and TRβ1 by 77% and 25%, respectively. It is primarily utilized in research related to arrhythmic conditions, providing insights into the mechanisms of thyroid hormone signaling in cardiac physiology.
Chemical Information
| Catalog Num | A85446 |
|---|---|
| M. Wt | 537.11 |
| Formula | C27H37ClN2O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 197431-02-0 |
| Synonyms | SR35021 hydrochloride |
| SMILES | O=C(C1=C(CCCC)OC2=C1C=C(NS(=O)(C)=O)C=C2)C3=CC=C(C=C3)OCCCNCCCC.Cl |
Biological Activity
| Description | Debutyldronedarone hydrochloride is a selective inhibitor of the thyroid hormone receptor α1 (TRα1), derived from the main metabolite of Dronedarone. This compound effectively inhibits T3 binding to TRα1 and TRβ1 by 77% and 25%, respectively. It is primarily utilized in research related to arrhythmic conditions, providing insights into the mechanisms of thyroid hormone signaling in cardiac physiology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
