Product Data Sheet
Liothyronine-13C6-1
Catalog No. A85457
Liothyronine-13C6-1 is a stable isotope-labeled form of Liothyronine, which serves as a potent agonist for thyroid hormone receptors TRα and TRβ, exhibiting inhibition constants (Kis) of 2.33 nM for both receptors. This reagent is valuable for research applications involving thyroid hormone signaling, metabolic studies, and metabolic disorders. Its isotopic labeling allows for enhanced tracking and quantification in various analytical techniques, facilitating investigations into hormone receptor activity and related biological pathways.
Chemical Information
| Catalog Num | A85457 |
|---|---|
| M. Wt | 656.93 |
| Formula | C913C6H12I3NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1213431-76-5 |
| Synonyms | Triiodothyronine-13C6-1; 3,3',5-Triiodo-L-thyronine-13C6-1; T3-13C6-1 |
| SMILES | I[13C]([13CH]=[13C]([13CH]=[13C]1I)C[C@H](N)C(O)=O)=[13C]1OC2=CC(I)=C(C=C2)O |
Biological Activity
| Description | Liothyronine-13C6-1 is a stable isotope-labeled form of Liothyronine, which serves as a potent agonist for thyroid hormone receptors TRα and TRβ, exhibiting inhibition constants (Kis) of 2.33 nM for both receptors. This reagent is valuable for research applications involving thyroid hormone signaling, metabolic studies, and metabolic disorders. Its isotopic labeling allows for enhanced tracking and quantification in various analytical techniques, facilitating investigations into hormone receptor activity and related biological pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
