Product Data Sheet

TRβ agonist 1

Catalog No. A85463

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TRβ agonist 1 is a selective agonist of the thyroid hormone receptor beta (TRβ), characterized by an EC50 of 21 nM. This compound demonstrates significant biological activity relevant to the study of dyslipidemia, nonalcoholic steatohepatitis (NASH), and resistance to thyroid hormone (RTH). Its mutation-sensitive properties make it an important tool for research into TRβ-related pathways and disorders.
Chemical Information
Catalog NumA85463
M. Wt548.52
FormulaC29H25FN2O8
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2770681-85-9
Synonyms
SMILESO=C(C1=C(C2=CC=C(C=C2C(OC)=N1)OC3=C(C=C(C=C3C)C(C4=CC(OC)=CC(F)=C4)=O)C)O)NCC(O)=O
Biological Activity
DescriptionTRβ agonist 1 is a selective agonist of the thyroid hormone receptor beta (TRβ), characterized by an EC50 of 21 nM. This compound demonstrates significant biological activity relevant to the study of dyslipidemia, nonalcoholic steatohepatitis (NASH), and resistance to thyroid hormone (RTH). Its mutation-sensitive properties make it an important tool for research into TRβ-related pathways and disorders.
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SHIPPING AND STORAGE
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