MLS000389544
Catalog No. A85484

MLS000389544 is a selective and potent antagonist of the thyroid hormone receptor beta (TRβ), effectively inhibiting its interaction with steroid receptor coactivator 2 (SRC2). This compound serves as a valuable tool in research related to thyroid hormone signaling, providing insights into the physiological and pathological roles of TRβ in various biological processes. Its application may extend to studies on metabolic disorders, cancer, and cardiovascular diseases, where TRβ signaling plays a crucial role.
Chemical Information
| Catalog Num | A85484 |
|---|---|
| M. Wt | 436.48 |
| Formula | C20H24N2O7S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 573965-48-7 |
| Synonyms | |
| SMILES | O=C(OCC(NC1(C2)CC3CC2CC(C3)C1)=O)C4=CC=C(S(=O)(C)=O)C([N+]([O-])=O)=C4 |
Biological Activity
| Description | MLS000389544 is a selective and potent antagonist of the thyroid hormone receptor beta (TRβ), effectively inhibiting its interaction with steroid receptor coactivator 2 (SRC2). This compound serves as a valuable tool in research related to thyroid hormone signaling, providing insights into the physiological and pathological roles of TRβ in various biological processes. Its application may extend to studies on metabolic disorders, cancer, and cardiovascular diseases, where TRβ signaling plays a crucial role. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


