Product Data Sheet

L-6424

Catalog No. A85491

main product photo
L-6424 is a selective inhibitor of triiodothyronine receptor (T3R) binding, specifically targeting alpha-1 (α1-T3R) and beta-1 (β1-T3R) receptors. Its primary mechanism interferes with T3 binding, making it a useful tool in research focused on thyroid hormone signaling pathways. This compound is applicable in studies investigating the role of T3R in metabolic regulation, cellular differentiation, and various endocrine disorders.
Chemical Information
Catalog NumA85491
M. Wt420.24
FormulaC19H17IO3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.147030-50-0
Synonyms
SMILESO=C(C1=CC=C(C(I)=C1)O)C2=C(OC3=CC=CC=C23)CCCC
Biological Activity
DescriptionL-6424 is a selective inhibitor of triiodothyronine receptor (T3R) binding, specifically targeting alpha-1 (α1-T3R) and beta-1 (β1-T3R) receptors. Its primary mechanism interferes with T3 binding, making it a useful tool in research focused on thyroid hormone signaling pathways. This compound is applicable in studies investigating the role of T3R in metabolic regulation, cellular differentiation, and various endocrine disorders.
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