A 274
Catalog No. A85498

A 274 is a thyroid hormone receptor inhibitor that functions as an analogue of amiodarone. It effectively inhibits the binding of triiodothyronine (T3) to both α1- and β1-thyroid hormone receptors in vitro, demonstrating significant potential for modulating thyroid hormone signaling. This compound can be utilized in research applications focused on thyroid function and its associated biochemical pathways.
Chemical Information
| Catalog Num | A85498 |
|---|---|
| M. Wt | 274.31 |
| Formula | C19H14O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 77273-75-7 |
| Synonyms | |
| SMILES | OC1=CC=C(C2C3=C(OC4=C2C=CC=C4)C=CC=C3)C=C1 |
Biological Activity
| Description | A 274 is a thyroid hormone receptor inhibitor that functions as an analogue of amiodarone. It effectively inhibits the binding of triiodothyronine (T3) to both α1- and β1-thyroid hormone receptors in vitro, demonstrating significant potential for modulating thyroid hormone signaling. This compound can be utilized in research applications focused on thyroid function and its associated biochemical pathways. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


