Product Data Sheet

CB1151

Catalog No. A85525

main product photo
CB1151 is a 20-epi analogue of 1,25-dihydroxyvitamin D3 (VD) that targets the vitamin D receptor (VDR). This compound demonstrates significant anti-tumor activity, effectively inhibiting the growth of MCF-7 breast cancer cells with an IC50 value of 0.82 nM. CB1151 is primarily utilized in research focusing on cancer biology and the mechanisms of vitamin D in therapeutic applications.
Chemical Information
Catalog NumA85525
M. Wt446.66
FormulaC28H46O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.182369-28-4
Synonyms
SMILESC[C@]1(CCC/2)[C@](CC[C@@H]1[C@@H](C)OCCC(CC)(CC)O)([H])C2=C\C=C(C[C@@H](O)C[C@@H]3O)/C3=C
Biological Activity
DescriptionCB1151 is a 20-epi analogue of 1,25-dihydroxyvitamin D3 (VD) that targets the vitamin D receptor (VDR). This compound demonstrates significant anti-tumor activity, effectively inhibiting the growth of MCF-7 breast cancer cells with an IC50 value of 0.82 nM. CB1151 is primarily utilized in research focusing on cancer biology and the mechanisms of vitamin D in therapeutic applications.
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SHIPPING AND STORAGE
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