Product Data Sheet
Ro-65-2299
Catalog No. A85544
Ro-65-2299 is an orally active vitamin D analogue that functions as a potential agonist of the vitamin D receptor (VDR), with an effective dose (ED50) of 180 nM. It promotes thickening of the epidermis and demonstrates antipsoriatic activity in hairless mice, with an ED50 of 7.5 mg/kg. This compound is suitable for research into inflammation and immunology, particularly in the context of psoriasis and related skin disorders.
Chemical Information
| Catalog Num | A85544 |
|---|---|
| M. Wt | 444.45 |
| Formula | C21H30F6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 241151-12-2 |
| Synonyms | |
| SMILES | O[C@H]1C[C@H](O)C/C(C1)=C/C=C/CCCC(C)(C)C/C=C\C(C(F)(F)F)(O)C(F)(F)F |
Biological Activity
| Description | Ro-65-2299 is an orally active vitamin D analogue that functions as a potential agonist of the vitamin D receptor (VDR), with an effective dose (ED50) of 180 nM. It promotes thickening of the epidermis and demonstrates antipsoriatic activity in hairless mice, with an ED50 of 7.5 mg/kg. This compound is suitable for research into inflammation and immunology, particularly in the context of psoriasis and related skin disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
