Product Data Sheet
19-Nor-22-oxa-1a,25(OH)2-VD3
Catalog No. A85546
19-Nor-22-oxa-1a,25(OH)2-VD3 is a vitamin D₃ analogue that exhibits low affinity for the vitamin D receptor (VDR) and minimal binding to the vitamin D binding protein (DBP). This compound effectively induces the differentiation of HL-60 cells and promotes G₀-G₁ phase cell cycle arrest. It serves as a valuable tool for investigating conditions such as excessive hyperparathyroidism in biological research.
Chemical Information
| Catalog Num | A85546 |
|---|---|
| M. Wt | 406.60 |
| Formula | C25H42O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 284041-36-7 |
| Synonyms | |
| SMILES | C[C@@]12[C@](CC[C@]2([H])[C@H](C)OCCC(C)(O)C)([H])/C(CCC1)=C/C=C3C[C@H](C[C@@H](C\3)O)O |
Biological Activity
| Description | 19-Nor-22-oxa-1a,25(OH)2-VD3 is a vitamin D₃ analogue that exhibits low affinity for the vitamin D receptor (VDR) and minimal binding to the vitamin D binding protein (DBP). This compound effectively induces the differentiation of HL-60 cells and promotes G₀-G₁ phase cell cycle arrest. It serves as a valuable tool for investigating conditions such as excessive hyperparathyroidism in biological research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
