Product Data Sheet
AcdK
Catalog No. A86142
AcdK is a non-natural amino acid that serves as a precursor to allysine. It facilitates site-specific incorporation into target proteins in Escherichia coli through the amber suppression strategy. AcdK supports the modification of target proteins via lysine dimethylation or monomethylation, enabling the synthesis of site-specific lysine-methylated variants of histone H3 and p53. This reagent is valuable for studying the substrate specificity and catalytic functions of epigenetic enzymes in various research applications.
Chemical Information
| Catalog Num | A86142 |
|---|---|
| M. Wt | 319.32 |
| Formula | C14H17N5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2097535-26-5 |
| Synonyms | |
| SMILES | OC([C@@H](N)CC/C=C/NC(OCC1=CC=C(C=C1)N=[N+]=[N-])=O)=O |
Biological Activity
| Description | AcdK is a non-natural amino acid that serves as a precursor to allysine. It facilitates site-specific incorporation into target proteins in Escherichia coli through the amber suppression strategy. AcdK supports the modification of target proteins via lysine dimethylation or monomethylation, enabling the synthesis of site-specific lysine-methylated variants of histone H3 and p53. This reagent is valuable for studying the substrate specificity and catalytic functions of epigenetic enzymes in various research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
