Product Data Sheet
EGTA
Catalog No. A86384
EGTA is a highly specific calcium ion chelator that operates by binding calcium ions with an apparent dissociation constant (Kd) of 60.5 nM at physiological pH (7.4). Its strong selectivity for Ca2+ over Mg2+ (with a Kd for Mg2+ ranging from 1-10 mM) makes it particularly valuable in research involving calcium signaling. EGTA is effective in inhibiting the substrate adherence capacity of inflammatory macrophages, making it useful in studying inflammatory responses and various cellular processes.
Chemical Information
| Catalog Num | A86384 |
|---|---|
| M. Wt | 380.35 |
| Formula | C14H24N2O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 67-42-5 |
| Synonyms | |
| SMILES | O=C(O)CN(CC(O)=O)CCOCCOCCN(CC(O)=O)CC(O)=O |
Biological Activity
| Description | EGTA is a highly specific calcium ion chelator that operates by binding calcium ions with an apparent dissociation constant (Kd) of 60.5 nM at physiological pH (7.4). Its strong selectivity for Ca2+ over Mg2+ (with a Kd for Mg2+ ranging from 1-10 mM) makes it particularly valuable in research involving calcium signaling. EGTA is effective in inhibiting the substrate adherence capacity of inflammatory macrophages, making it useful in studying inflammatory responses and various cellular processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
