Product Data Sheet

Sodium iodoacetate

Catalog No. A86398

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Sodium iodoacetate is a specific inhibitor of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), effectively disrupting glycolytic pathways. This compound is utilized in research to study the mechanisms of glucose metabolism and its implications in various diseases. Additionally, sodium iodoacetate has been employed to induce osteoarthritis and associated pain models in experimental animal studies, providing valuable insights into joint pathophysiology.
Chemical Information
Catalog NumA86398
M. Wt207.93
FormulaC2H2INaO2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.305-53-3
SynonymsIodoacetic acid sodium salt
SMILESO=C(O[Na])CI
Biological Activity
DescriptionSodium iodoacetate is a specific inhibitor of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), effectively disrupting glycolytic pathways. This compound is utilized in research to study the mechanisms of glucose metabolism and its implications in various diseases. Additionally, sodium iodoacetate has been employed to induce osteoarthritis and associated pain models in experimental animal studies, providing valuable insights into joint pathophysiology.
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