Product Data Sheet
Pimonidazole hydrochloride
Catalog No. A86417
Pimonidazole hydrochloride is a hypoxia marker that covalently binds to macromolecules in hypoxic cells, allowing for both qualitative and quantitative assessment of tumor hypoxia. Upon reduction of its nitro group, it forms reductive metabolites, further aiding in the study of tumor microenvironments and cell proliferation. This reagent is valuable for researchers investigating the effects of hypoxia on tumor progression and therapeutic resistance.
Chemical Information
| Catalog Num | A86417 |
|---|---|
| M. Wt | 290.75 |
| Formula | C11H19ClN4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 70132-51-3 |
| Synonyms | |
| SMILES | OC(CN1C=CN=C1[N+]([O-])=O)CN2CCCCC2.Cl |
Biological Activity
| Description | Pimonidazole hydrochloride is a hypoxia marker that covalently binds to macromolecules in hypoxic cells, allowing for both qualitative and quantitative assessment of tumor hypoxia. Upon reduction of its nitro group, it forms reductive metabolites, further aiding in the study of tumor microenvironments and cell proliferation. This reagent is valuable for researchers investigating the effects of hypoxia on tumor progression and therapeutic resistance. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
