Product Data Sheet
Phosphatidylglycerols (egg) sodium salt
Catalog No. A86448
Phosphatidylglycerols (egg) sodium salt is a biochemical assay reagent that selectively targets the TLR4 accessory protein CD14/MD-2 complex, effectively inhibiting LPS or virus-mediated inflammatory signaling pathways through competitive binding. This compound directly interacts with viral particles, blocking infection and reducing COX-2 expression to lower the release of inflammatory cytokines such as IL-6 and IL-8. Additionally, it enhances oxidative stress response by promoting mitochondrial membrane phospholipid remodeling. Phosphatidylglycerols are applicable in research related to chronic inflammatory diseases, including atherosclerosis, and respiratory viral infections such as RSV.
Chemical Information
| Catalog Num | A86448 |
|---|---|
| M. Wt | 783.04 |
| Formula | C42H80NaO9P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 383907-64-0 |
| Synonyms | Egg PG |
| SMILES | CCCCCCCCCCCCCCCC(OC[C@](CC(CCCCCCC/C=C\CCCCCCCC)=O)(C)COP(OCC(O)CO)(O[Na])=O)=O |
Biological Activity
| Description | Phosphatidylglycerols (egg) sodium salt is a biochemical assay reagent that selectively targets the TLR4 accessory protein CD14/MD-2 complex, effectively inhibiting LPS or virus-mediated inflammatory signaling pathways through competitive binding. This compound directly interacts with viral particles, blocking infection and reducing COX-2 expression to lower the release of inflammatory cytokines such as IL-6 and IL-8. Additionally, it enhances oxidative stress response by promoting mitochondrial membrane phospholipid remodeling. Phosphatidylglycerols are applicable in research related to chronic inflammatory diseases, including atherosclerosis, and respiratory viral infections such as RSV. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
