Product Data Sheet
Ac4GlcNAz
Catalog No. A86564
Ac4GlcNAz, an azido-tagged analogue of N-acetylglucosamine (GlcNAc), serves as a biochemical assay reagent with a primary mechanism of action involving the hexosamine biosynthetic pathway. It is designed with azide functionality on the N-acyl side chain and is acetylated to enhance cell membrane permeability. Once inside the cell, Ac4GlcNAz is deacetylated, allowing it to participate in glycosylation processes. The resultant modified proteins can be labeled with fluorescent tags via Cu(I)-catalyzed azide-alkyne cycloaddition, facilitating detection and analysis in various research applications.
Chemical Information
| Catalog Num | A86564 |
|---|---|
| M. Wt | 430.37 |
| Formula | C16H22N4O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 98924-81-3 |
| Synonyms | N-azidoacetylglucosamine-tetraacylated |
| SMILES | CC(O[C@@H]1[C@H](C(O[C@@H]([C@H]1OC(C)=O)COC(C)=O)OC(C)=O)NC(CN=[N+]=[N-])=O)=O |
Biological Activity
| Description | Ac4GlcNAz, an azido-tagged analogue of N-acetylglucosamine (GlcNAc), serves as a biochemical assay reagent with a primary mechanism of action involving the hexosamine biosynthetic pathway. It is designed with azide functionality on the N-acyl side chain and is acetylated to enhance cell membrane permeability. Once inside the cell, Ac4GlcNAz is deacetylated, allowing it to participate in glycosylation processes. The resultant modified proteins can be labeled with fluorescent tags via Cu(I)-catalyzed azide-alkyne cycloaddition, facilitating detection and analysis in various research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
