Product Data Sheet
5β,6β-epoxycholestanol
Catalog No. A86970
5β,6β-epoxycholestanol is an oxidative metabolite of cholesterol that targets cellular oxidative stress pathways. It has been shown to induce lactate dehydrogenase (LDH) release and promote apoptosis in macrophage-differentiated U937 cells. This compound is particularly relevant in studies of atherosclerosis, as it has been identified in human fatty streaks and advanced atherosclerotic lesions, providing insight into cholesterol metabolism and its implications in cardiovascular disease.
Chemical Information
| Catalog Num | A86970 |
|---|---|
| M. Wt | 402.65 |
| Formula | C27H46O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 4025-59-6 |
| Synonyms | Cholesterol 5beta,6beta-epoxide |
| SMILES | C[C@]12[C@@]3(C[C@H](CC2)O)[C@](C[C@]4([H])[C@]1([H])CC[C@]5([C@@]4([H])CC[C@]5([H])[C@H](C)CCCC(C)C)C)([H])O3 |
Biological Activity
| Description | 5β,6β-epoxycholestanol is an oxidative metabolite of cholesterol that targets cellular oxidative stress pathways. It has been shown to induce lactate dehydrogenase (LDH) release and promote apoptosis in macrophage-differentiated U937 cells. This compound is particularly relevant in studies of atherosclerosis, as it has been identified in human fatty streaks and advanced atherosclerotic lesions, providing insight into cholesterol metabolism and its implications in cardiovascular disease. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
