Product Data Sheet
(2E)-TCO-PNB ester
Catalog No. A87313
(2E)-TCO-PNB ester functions as a Click Amino Acid and serves as a versatile linker for the synthesis of PROTAC molecules. Its unique TCO group can participate in an inverse electron demand Diels-Alder reaction (iEDDA) with tetrazine-containing compounds, facilitating efficient conjugation in bioconjugation strategies. This reagent is suitable for applications in chemical biology, enabling the development of targeted therapeutics and advanced biomolecular constructs.
Chemical Information
| Catalog Num | A87313 |
|---|---|
| M. Wt | 291.30 |
| Formula | C15H17NO5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1580501-97-8 |
| Synonyms | |
| SMILES | O=C(OC1=CC=C([N+]([O-])=O)C=C1)OC2/C=C/CCCCC2 |
Biological Activity
| Description | (2E)-TCO-PNB ester functions as a Click Amino Acid and serves as a versatile linker for the synthesis of PROTAC molecules. Its unique TCO group can participate in an inverse electron demand Diels-Alder reaction (iEDDA) with tetrazine-containing compounds, facilitating efficient conjugation in bioconjugation strategies. This reagent is suitable for applications in chemical biology, enabling the development of targeted therapeutics and advanced biomolecular constructs. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
