Product Data Sheet

TCO-PNB ester

Catalog No. A87622

main product photo
TCO-PNB ester is an amine-reactive building block designed for the modification of amine-containing molecules. It features a strained trans-cyclooctene (TCO) group that participates in an inverse electron demand Diels-Alder reaction (iEDDA) with tetrazine-containing compounds. This reagent is valuable for applications in bioconjugation, enabling precise labeling and modification of biomolecules for use in various biochemical studies and therapeutic developments.
Chemical Information
Catalog NumA87622
M. Wt291.30
FormulaC15H17NO5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1438415-89-4
Synonyms
SMILESO=C(OC1=CC=C([N+]([O-])=O)C=C1)O[C@H]2CC/C=C/CCC2
Biological Activity
DescriptionTCO-PNB ester is an amine-reactive building block designed for the modification of amine-containing molecules. It features a strained trans-cyclooctene (TCO) group that participates in an inverse electron demand Diels-Alder reaction (iEDDA) with tetrazine-containing compounds. This reagent is valuable for applications in bioconjugation, enabling precise labeling and modification of biomolecules for use in various biochemical studies and therapeutic developments.
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