Tetramethylammonium fluoride tetrahydrate
Catalog No. A87708

Tetramethylammonium fluoride tetrahydrate (TMAF) functions as a quaternary ammonium salt and serves as a weak base and fluoride ion source in various organic reactions. Its versatility allows for applications in nucleophilic substitution, functional group deprotection, and ring-opening polymerization, while being compatible with numerous functional groups. TMAF is also employed as a fluorinating agent in medicinal chemistry for radiotracer preparation and protein modification in biochemistry. The tetrahydrate form enhances stability and handling compared to the anhydrous variant, making it an essential reagent in synthetic chemistry.
Chemical Information
| Catalog Num | A87708 |
|---|---|
| M. Wt | 165.20 |
| Formula | C4H20FNO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 17787-40-5 |
| Synonyms | |
| SMILES | C[N+](C)(C)C.[F-].O.O.O.O |
Biological Activity
| Description | Tetramethylammonium fluoride tetrahydrate (TMAF) functions as a quaternary ammonium salt and serves as a weak base and fluoride ion source in various organic reactions. Its versatility allows for applications in nucleophilic substitution, functional group deprotection, and ring-opening polymerization, while being compatible with numerous functional groups. TMAF is also employed as a fluorinating agent in medicinal chemistry for radiotracer preparation and protein modification in biochemistry. The tetrahydrate form enhances stability and handling compared to the anhydrous variant, making it an essential reagent in synthetic chemistry. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


