Indacrinone
Catalog No. A88572

Indacrinone is a potent diuretic that primarily targets renal transport mechanisms, exhibiting significant saluretic activity. In preclinical studies, it has demonstrated pronounced saluretic effects in rat and dog models, along with both uricosuric and saluretic properties in chimpanzees. This compound is valuable for research applications focusing on kidney function and electrolyte balance. Its unique pharmacological profile offers insights into diuretic mechanisms and potential therapeutic uses in renal disorders.
Chemical Information
| Catalog Num | A88572 |
|---|---|
| M. Wt | 365.21 |
| Formula | C18H14Cl2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 56049-88-8 |
| Synonyms | MK-196; Indacrynic acid |
| SMILES | O=C(O)COC1=CC2=C(C(C(C3=CC=CC=C3)(C)C2)=O)C(Cl)=C1Cl |
Biological Activity
| Description | Indacrinone is a potent diuretic that primarily targets renal transport mechanisms, exhibiting significant saluretic activity. In preclinical studies, it has demonstrated pronounced saluretic effects in rat and dog models, along with both uricosuric and saluretic properties in chimpanzees. This compound is valuable for research applications focusing on kidney function and electrolyte balance. Its unique pharmacological profile offers insights into diuretic mechanisms and potential therapeutic uses in renal disorders. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


