Product Data Sheet
BMVC4
Catalog No. A88993
BMVC4 is a G-quadruplex (G4) stabilizer specifically targeting the human telomeric sequence d[AG3(T2AG3)3]. This compound exhibits enhanced suitability as a core molecule for G4 stabilizers and demonstrates significant potential for anticancer research applications. Using circular dichroism (CD) spectroscopy, BMVC4 shows improved stability compared to other derivatives in the presence of trivalent cations. Additionally, a rapid screening method utilizing Cu2+-induced G4 unfolding can be employed to identify superior G4 stabilizers, emphasizing BMVC4's role as a promising candidate for further study in therapeutic settings.
Chemical Information
| Catalog Num | A88993 |
|---|---|
| M. Wt | 659.30 |
| Formula | C26H23I2N5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 868843-84-9 |
| Synonyms | |
| SMILES | C[N+]1=CC(/C=C/C2=CC3=C(NC4=C3C=C(/C=C/C5=NC=C[N+](C)=C5)C=C4)C=C2)=NC=C1.[I-].[I-] |
Biological Activity
| Description | BMVC4 is a G-quadruplex (G4) stabilizer specifically targeting the human telomeric sequence d[AG3(T2AG3)3]. This compound exhibits enhanced suitability as a core molecule for G4 stabilizers and demonstrates significant potential for anticancer research applications. Using circular dichroism (CD) spectroscopy, BMVC4 shows improved stability compared to other derivatives in the presence of trivalent cations. Additionally, a rapid screening method utilizing Cu2+-induced G4 unfolding can be employed to identify superior G4 stabilizers, emphasizing BMVC4's role as a promising candidate for further study in therapeutic settings. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
