1-Piperonylpiperazine
Catalog No. A89230

1-Piperonylpiperazine is a biochemical reagent known for its role in the metabolism of psychoactive substances. It undergoes metabolic processes including demethylenation and methylation, leading to the formation of N-(4-hydroxy-3-methoxybenzyl)piperazine and its subsequent conjugation through glucuronidation or sulfation. This compound has demonstrated the capability to alter the disposition and metabolism of 3,4-methylenedioxymethamphetamine (MDMA) in both the brain and peripheral organs, while also exhibiting protective effects against MDMA-induced neurotoxicity. Its applications span various fields of pharmacology and toxicology research.
Chemical Information
| Catalog Num | A89230 |
|---|---|
| M. Wt | 220.27 |
| Formula | C12H16N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 32231-06-4 |
| Synonyms | MDBP |
| SMILES | C1(CN2CCNCC2)=CC3=C(OCO3)C=C1 |
Biological Activity
| Description | 1-Piperonylpiperazine is a biochemical reagent known for its role in the metabolism of psychoactive substances. It undergoes metabolic processes including demethylenation and methylation, leading to the formation of N-(4-hydroxy-3-methoxybenzyl)piperazine and its subsequent conjugation through glucuronidation or sulfation. This compound has demonstrated the capability to alter the disposition and metabolism of 3,4-methylenedioxymethamphetamine (MDMA) in both the brain and peripheral organs, while also exhibiting protective effects against MDMA-induced neurotoxicity. Its applications span various fields of pharmacology and toxicology research. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


