Product Data Sheet

Sialyl Lewis A

Catalog No. A89247

main product photo
Sialyl Lewis A (SLeA) is a carbohydrate antigen that targets sialylated molecules, functioning as a significant tumor marker. Its upregulation is associated with various malignancies, including cervical, pancreatic, and colon cancers, where it plays a crucial role in tumor cell migration and adhesion. Additionally, elevated Sialyl Lewis A expression has been linked to pregnancy complications, making it a valuable target for research in cancer biology and reproductive health.
Chemical Information
Catalog NumA89247
M. Wt820.75
FormulaC31H52N2O23
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.92448-22-1
SynonymsSLeA
SMILESOC([C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)O[C@@H]2[C@H]([C@@H](O[C@@H]([C@@H]2O)CO)O[C@H]([C@H](C=O)NC(C)=O)[C@@H]([C@H](O)CO)O[C@H]3[C@H]([C@@H]([C@@H]([C@@H](O3)C)O)O)O)O)=O
Biological Activity
DescriptionSialyl Lewis A (SLeA) is a carbohydrate antigen that targets sialylated molecules, functioning as a significant tumor marker. Its upregulation is associated with various malignancies, including cervical, pancreatic, and colon cancers, where it plays a crucial role in tumor cell migration and adhesion. Additionally, elevated Sialyl Lewis A expression has been linked to pregnancy complications, making it a valuable target for research in cancer biology and reproductive health.
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SHIPPING AND STORAGE
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