Product Data Sheet
Ceramide 3-d3
Catalog No. A89377
Ceramide 3-d3 (N-Stearoyl phytosphingosine-d3) is a deuterated form of Ceramide 3, a bioactive sphingolipid notably present in the stratum corneum of Saccharomyces cerevisiae, wheat grain, and mammalian epidermis. With a phytosphingosine backbone linked to a C18 fatty acid chain, Ceramide 3-d3 plays a crucial role in regulating apoptosis and cell differentiation, while also supporting smooth muscle cell proliferation and inhibiting the mitochondrial respiratory chain. Furthermore, it suppresses the expression of pro-inflammatory cytokines IL-4 and TNF-α, as well as transcription factors c-Jun and NF-κB in histone-stimulated mouse skin tissue, making it valuable for research in skin health and inflammation.
Chemical Information
| Catalog Num | A89377 |
|---|---|
| M. Wt | 586.99 |
| Formula | C36H70D3NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1354806-91-9 |
| Synonyms | N-Stearoyl phytosphingosine-d3 |
| SMILES | OC[C@@H]([C@H](O)[C@H](O)CCCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCCCC([2H])([2H])[2H])=O |
Biological Activity
| Description | Ceramide 3-d3 (N-Stearoyl phytosphingosine-d3) is a deuterated form of Ceramide 3, a bioactive sphingolipid notably present in the stratum corneum of Saccharomyces cerevisiae, wheat grain, and mammalian epidermis. With a phytosphingosine backbone linked to a C18 fatty acid chain, Ceramide 3-d3 plays a crucial role in regulating apoptosis and cell differentiation, while also supporting smooth muscle cell proliferation and inhibiting the mitochondrial respiratory chain. Furthermore, it suppresses the expression of pro-inflammatory cytokines IL-4 and TNF-α, as well as transcription factors c-Jun and NF-κB in histone-stimulated mouse skin tissue, making it valuable for research in skin health and inflammation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
