Product Data Sheet
(±)15-HEPE
Catalog No. A92934
(±)15-HEPE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEPE and 15(S)-HEPE, functioning primarily as an ester product. It demonstrates antimicrobial activity against P. acnes and S. aureus, with MIC values of 128 and 512 mg/L, respectively. Additionally, (±)15-HEPE effectively inhibits the aggregation of isolated rat neutrophils induced by the formyl peptide receptor agonist fMLP, with an IC50 of 4.7 µM. Elevated levels of (±)15-HEPE in bronchoalveolar lavage fluid correlate with conditions such as allergic asthma and COVID-19, highlighting its potential relevance in respiratory research.
Chemical Information
| Catalog Num | A92934 |
|---|---|
| M. Wt | 318.45 |
| Formula | C20H30O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 88852-33-9 |
| Synonyms | (±)15-hydroxyeicosapentaenoic acid; 15-OHEPA |
| SMILES | CC/C=C\CC(O)/C=C/C=C\C/C=C\C/C=C\CCCC(O)=O |
Biological Activity
| Description | (±)15-HEPE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEPE and 15(S)-HEPE, functioning primarily as an ester product. It demonstrates antimicrobial activity against P. acnes and S. aureus, with MIC values of 128 and 512 mg/L, respectively. Additionally, (±)15-HEPE effectively inhibits the aggregation of isolated rat neutrophils induced by the formyl peptide receptor agonist fMLP, with an IC50 of 4.7 µM. Elevated levels of (±)15-HEPE in bronchoalveolar lavage fluid correlate with conditions such as allergic asthma and COVID-19, highlighting its potential relevance in respiratory research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
