Product Data Sheet
Florbenazine
Catalog No. A92949
Florbenazine is a diagnostic imaging agent that selectively targets the vesicular monoamine transporter 2 (VMAT2) in the central nervous system. The fluorine-18 labeled derivative is utilized in positron emission tomography (PET) scanning to assess neuromodulatory functions. Research has demonstrated a significant biodistribution profile in mice, with a high striatum-to-cerebellum ratio, supporting its application in the diagnostic investigation of neurodegenerative disorders, such as dementia with Lewy bodies and Parkinson’s disease.
Chemical Information
| Catalog Num | A92949 |
|---|---|
| M. Wt | 365.48 |
| Formula | C21H32FNO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 937245-42-6 |
| Synonyms | AV-133 |
| SMILES | COC1=C(OCCCF)C=C2CCN(C[C@H]([C@@H](C3)O)CC(C)C)[C@@]3([H])C2=C1 |
Biological Activity
| Description | Florbenazine is a diagnostic imaging agent that selectively targets the vesicular monoamine transporter 2 (VMAT2) in the central nervous system. The fluorine-18 labeled derivative is utilized in positron emission tomography (PET) scanning to assess neuromodulatory functions. Research has demonstrated a significant biodistribution profile in mice, with a high striatum-to-cerebellum ratio, supporting its application in the diagnostic investigation of neurodegenerative disorders, such as dementia with Lewy bodies and Parkinson’s disease. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
