Product Data Sheet

Trimebutine (3-TCBS)

Catalog No. A93297

main product photo
Trimebutine (3-TCBS) is a novel hydrogen sulfide (H2S) releasing reagent that combines trimebutine with phenyl 3-thiocarbamate to enhance anti-nociceptive properties. It demonstrates significant efficacy in reducing visceral pain and discomfort in vivo, particularly in a mouse colonic distension model. This compound’s ability to release H2S in a dose-dependent manner suggests its potential for research applications focused on pain management and gastrointestinal disorders.
Chemical Information
Catalog NumA93297
M. Wt604.73
FormulaC29H36N2O8S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1456509-46-8
SynonymsGIC-1001
SMILESO=C(C1=CC(OC)=C(C(OC)=C1)OC)OCC(N(C)C)(CC)C2=CC=CC=C2.O=S(C3=CC=CC(C(N)=S)=C3)(O)=O
Biological Activity
DescriptionTrimebutine (3-TCBS) is a novel hydrogen sulfide (H2S) releasing reagent that combines trimebutine with phenyl 3-thiocarbamate to enhance anti-nociceptive properties. It demonstrates significant efficacy in reducing visceral pain and discomfort in vivo, particularly in a mouse colonic distension model. This compound’s ability to release H2S in a dose-dependent manner suggests its potential for research applications focused on pain management and gastrointestinal disorders.
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SHIPPING AND STORAGE
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