Product Data Sheet
N-(TCO)-N-bis(PEG4-acid)
Catalog No. A93519
N-(TCO)-N-bis(PEG4-acid) is a versatile click chemistry reagent featuring a terminal trans-cyclooctene (TCO) group and two terminal carboxylic acid moieties. This compound facilitates the formation of stable covalent bonds through inverse-electron demand Diels-Alder cycloaddition with tetrazine-containing molecules, representing one of the fastest and most selective bioorthogonal reactions. The carboxylic acids can also efficiently react with primary amino groups in the presence of common coupling activators, such as EDC or HATU, making this reagent suitable for various biochemical assays and labeling applications in research settings.
Chemical Information
| Catalog Num | A93519 |
|---|---|
| M. Wt | 665.77 |
| Formula | C31H55NO14 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2644769-96-8 |
| Synonyms | |
| SMILES | O=C(O)CCOCCOCCOCCOCCN(C(=O)OC1CCC=CCCC1)CCOCCOCCOCCOCCC(=O)O |
Biological Activity
| Description | N-(TCO)-N-bis(PEG4-acid) is a versatile click chemistry reagent featuring a terminal trans-cyclooctene (TCO) group and two terminal carboxylic acid moieties. This compound facilitates the formation of stable covalent bonds through inverse-electron demand Diels-Alder cycloaddition with tetrazine-containing molecules, representing one of the fastest and most selective bioorthogonal reactions. The carboxylic acids can also efficiently react with primary amino groups in the presence of common coupling activators, such as EDC or HATU, making this reagent suitable for various biochemical assays and labeling applications in research settings. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
