Product Data Sheet
CbzNH-PEG4-CH2COOH
Catalog No. A93934
CbzNH-PEG4-CH2COOH is a PEG-based linker featuring a carboxylic acid group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer enhances the solubility of compounds in aqueous environments. The terminal carboxylic acid readily reacts with primary amines, particularly in the presence of activators like HATU, facilitating the formation of stable amide bonds. Furthermore, the benzyl protecting group can be effectively removed through hydrogenolysis, yielding a free amine for subsequent reactions. This reagent is valuable for a variety of biochemical assays and compound modification applications.
Chemical Information
| Catalog Num | A93934 |
|---|---|
| M. Wt | 385.41 |
| Formula | C18H27NO8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1451362-51-8 |
| Synonyms | |
| SMILES | O=C(O)COCCOCCOCCOCCNC(=O)OCC1=CC=CC=C1 |
Biological Activity
| Description | CbzNH-PEG4-CH2COOH is a PEG-based linker featuring a carboxylic acid group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer enhances the solubility of compounds in aqueous environments. The terminal carboxylic acid readily reacts with primary amines, particularly in the presence of activators like HATU, facilitating the formation of stable amide bonds. Furthermore, the benzyl protecting group can be effectively removed through hydrogenolysis, yielding a free amine for subsequent reactions. This reagent is valuable for a variety of biochemical assays and compound modification applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
