Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane
Catalog No. A94353

Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane is a versatile click chemistry reagent designed for biochemical assays, featuring three carboxylic acid groups and a methyltetrazine moiety. It facilitates the formation of stable covalent bonds with TCO-containing compounds through a highly selective inverse-electron demand Diels-Alder cycloaddition reaction, eliminating the need for catalysis or elevated temperatures. Additionally, the terminal carboxylic acid can efficiently couple with primary amines in the presence of activators such as EDC or HATU, forming stable amide bonds for a variety of bioconjugation applications in chemical and biological research.
Chemical Information
| Catalog Num | A94353 |
|---|---|
| M. Wt | 447.44 |
| Formula | C20H25N5O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2698339-32-9 |
| Synonyms | |
| SMILES | O=C(CCOCC(COCCC(O)=O)NC(CC1=CC=C(C2=NN=C(C)N=N2)C=C1)=O)O |
Biological Activity
| Description | Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane is a versatile click chemistry reagent designed for biochemical assays, featuring three carboxylic acid groups and a methyltetrazine moiety. It facilitates the formation of stable covalent bonds with TCO-containing compounds through a highly selective inverse-electron demand Diels-Alder cycloaddition reaction, eliminating the need for catalysis or elevated temperatures. Additionally, the terminal carboxylic acid can efficiently couple with primary amines in the presence of activators such as EDC or HATU, forming stable amide bonds for a variety of bioconjugation applications in chemical and biological research. |
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RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


