Product Data Sheet
Val-CDCA
Catalog No. A95247
Val-CDCA is a conjugate of chenodeoxycholate (CDCA) and C-24 L-Valine, primarily targeting the sodium-taurocholate cotransporting polypeptide (NTCP). This compound effectively inhibits taurocholate uptake in human NTCP-stably transfected HEK293 cells, indicating its potential utility in research related to hepatitis B virus (HBV) infection. Val-CDCA serves as a valuable tool for studies investigating bile acid transport and its implications in liver diseases.
Chemical Information
| Catalog Num | A95247 |
|---|---|
| M. Wt | 491.70 |
| Formula | C29H49NO5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1640013-00-8 |
| Synonyms | |
| SMILES | O[C@H]1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCC(N[C@H](C(O)=O)C(C)C)=O)C)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C1)C |
Biological Activity
| Description | Val-CDCA is a conjugate of chenodeoxycholate (CDCA) and C-24 L-Valine, primarily targeting the sodium-taurocholate cotransporting polypeptide (NTCP). This compound effectively inhibits taurocholate uptake in human NTCP-stably transfected HEK293 cells, indicating its potential utility in research related to hepatitis B virus (HBV) infection. Val-CDCA serves as a valuable tool for studies investigating bile acid transport and its implications in liver diseases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
