9,11-Methane-epoxy prostaglandin F1α
Catalog No. A95887

9,11-Methane-epoxy prostaglandin F1α is a derivative of prostaglandin H1 that targets various smooth muscle tissues. It effectively induces platelet aggregation in isolated rabbit platelets (EC50=0.88 µM) and promotes contraction in rabbit aortic strips (EC50=0.11 µM). Additionally, 9,11-methane-epoxy prostaglandin F1α demonstrates significant contractile activity in isolated guinea pig tracheas (EC50=3.4 µM). This compound is valuable for research applications related to cardiovascular and respiratory pharmacology.
Chemical Information
| Catalog Num | A95887 |
|---|---|
| M. Wt | 352.51 |
| Formula | C21H36O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 72517-81-8 |
| Synonyms | 9,11-Epoxymethano PGH1; 9,11-methane-epoxy PGF1α |
| SMILES | OC(CCCCCC[C@H]1[C@@H]([C@]2([H])C[C@@]1([H])CO2)/C=C/[C@H](O)CCCCC)=O |
Biological Activity
| Description | 9,11-Methane-epoxy prostaglandin F1α is a derivative of prostaglandin H1 that targets various smooth muscle tissues. It effectively induces platelet aggregation in isolated rabbit platelets (EC50=0.88 µM) and promotes contraction in rabbit aortic strips (EC50=0.11 µM). Additionally, 9,11-methane-epoxy prostaglandin F1α demonstrates significant contractile activity in isolated guinea pig tracheas (EC50=3.4 µM). This compound is valuable for research applications related to cardiovascular and respiratory pharmacology. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


