7-Descarbamoyl-17-amino geldanamycin
Catalog No. A96155

7-Descarbamoyl-17-amino geldanamycin is a derivative of Geldanamycin, targeting the heat shock protein 90 (HSP90). This compound demonstrates limited activity in the degradation of the p185erbB-2 protein within human breast cancer cells in vitro. It serves as a useful tool for investigating the role of HSP90 inhibition in cancer biology and can aid in the development of therapeutic strategies against breast cancer.
Chemical Information
| Catalog Num | A96155 |
|---|---|
| M. Wt | 502.60 |
| Formula | C27H38N2O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 169564-26-5 |
| Synonyms | |
| SMILES | C[C@H]1C[C@H](OC)[C@H](O)[C@@H](C)/C=C(C)/[C@H](O)[C@@H](OC)/C=C/C=C(C)/C(NC2=CC(C(N)=C(C2=O)C1)=O)=O |
Biological Activity
| Description | 7-Descarbamoyl-17-amino geldanamycin is a derivative of Geldanamycin, targeting the heat shock protein 90 (HSP90). This compound demonstrates limited activity in the degradation of the p185erbB-2 protein within human breast cancer cells in vitro. It serves as a useful tool for investigating the role of HSP90 inhibition in cancer biology and can aid in the development of therapeutic strategies against breast cancer. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


