Product Data Sheet
DT-678
Catalog No. A96744
DT-678 is an orally active antiplatelet agent that functions as an antithrombotic inhibitor. This compound is a conjugate formed by linking the active metabolite of Clopidogrel with 3-nitropyridine-2-thiol through a mixed disulfide bond. Unlike Clopidogrel, DT-678 does not depend on CYP2C19 for activation; instead, it directly releases active agents via thiol exchange reactions in vivo, demonstrating enhanced efficacy. DT-678 is valuable for research applications related to acute coronary syndrome and thrombosis.
Chemical Information
| Catalog Num | A96744 |
|---|---|
| M. Wt | 509.98 |
| Formula | C21H20ClN3O6S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2230703-82-7 |
| Synonyms | |
| SMILES | O=C(OC)C(C1=C(Cl)C=CC=C1)N(C/C2=C/C(O)=O)CCC2SSC3=NC=CC=C3[N+]([O-])=O |
Biological Activity
| Description | DT-678 is an orally active antiplatelet agent that functions as an antithrombotic inhibitor. This compound is a conjugate formed by linking the active metabolite of Clopidogrel with 3-nitropyridine-2-thiol through a mixed disulfide bond. Unlike Clopidogrel, DT-678 does not depend on CYP2C19 for activation; instead, it directly releases active agents via thiol exchange reactions in vivo, demonstrating enhanced efficacy. DT-678 is valuable for research applications related to acute coronary syndrome and thrombosis. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
