Product Data Sheet

(R)-ML375

Catalog No. B10859

main product photo
(R)-ML375 is an enantiomer of ML375, primarily targeting the muscarinic acetylcholine receptor subtype M5 (hM5). This compound is characterized by its lack of significant activity on M5 mAChR, exhibiting an IC50 greater than 30 μM. (R)-ML375 is suitable for studies exploring the role of muscarinic receptors in physiological and pathological processes, providing a valuable tool for chemical research in neuronal signaling and related fields.
Chemical Information
Catalog NumB10859
M. Wt424.83
FormulaC23H15ClF2N2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1488362-56-6
Synonyms(R)-VU0483253
SMILESO=C1N2[C@](N(C(C3=CC=C(F)C(F)=C3)=O)CC2)(C4=CC=C(Cl)C=C4)C5=C1C=CC=C5
Biological Activity
Description(R)-ML375 is an enantiomer of ML375, primarily targeting the muscarinic acetylcholine receptor subtype M5 (hM5). This compound is characterized by its lack of significant activity on M5 mAChR, exhibiting an IC50 greater than 30 μM. (R)-ML375 is suitable for studies exploring the role of muscarinic receptors in physiological and pathological processes, providing a valuable tool for chemical research in neuronal signaling and related fields.
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SHIPPING AND STORAGE
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