Product Data Sheet
NNMT-IN-4
Catalog No. B10997
NNMT-IN-4 is a selective and uncompetitive inhibitor of nicotinamide N-methyltransferase (NNMT) with demonstrated membrane permeability. It exhibits IC50 values of 42 nM in biochemical assays and 38 nM in cell-based assays, indicating potent inhibition. With favorable pharmacokinetic and pharmacodynamic profiles, along with excellent oral bioavailability, NNMT-IN-4 serves as a valuable in vivo chemical probe for NNMT research applications.
Chemical Information
| Catalog Num | B10997 |
|---|---|
| M. Wt | 177.20 |
| Formula | C9H11N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2947393-64-6 |
| Synonyms | |
| SMILES | C[C@@H]1CC2=C(N1)N=CC(C(N)=O)=C2 |
Biological Activity
| Description | NNMT-IN-4 is a selective and uncompetitive inhibitor of nicotinamide N-methyltransferase (NNMT) with demonstrated membrane permeability. It exhibits IC50 values of 42 nM in biochemical assays and 38 nM in cell-based assays, indicating potent inhibition. With favorable pharmacokinetic and pharmacodynamic profiles, along with excellent oral bioavailability, NNMT-IN-4 serves as a valuable in vivo chemical probe for NNMT research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
