Product Data Sheet
LysoFP-NO2
Catalog No. B11087
LysoFP-NO2 is a turn-on fluorescent probe specifically designed for the detection of carbon monoxide (CO) in lysosomal compartments. Upon interaction with lysosomal CO, LysoFP-NO2 is converted to the highly fluorescent LysoFP-NH2, enabling enhanced detection capabilities. This probe exhibits remarkable selectivity for CO, distinguishing it from various reactive nitrogen, oxygen, and sulfur species. It has excitation and emission maxima at 440 nm and 528 nm, respectively, and demonstrates low cytotoxicity in HepG2 cells at a concentration of 30 μM for up to five hours, making it suitable for various cellular imaging applications.
Chemical Information
| Catalog Num | B11087 |
|---|---|
| M. Wt | 355.34 |
| Formula | C18H17N3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 69408-75-9 |
| Synonyms | |
| SMILES | O=C1N(CCN2CCOCC2)C(C3=CC([N+]([O-])=O)=CC4=CC=CC1=C34)=O |
Biological Activity
| Description | LysoFP-NO2 is a turn-on fluorescent probe specifically designed for the detection of carbon monoxide (CO) in lysosomal compartments. Upon interaction with lysosomal CO, LysoFP-NO2 is converted to the highly fluorescent LysoFP-NH2, enabling enhanced detection capabilities. This probe exhibits remarkable selectivity for CO, distinguishing it from various reactive nitrogen, oxygen, and sulfur species. It has excitation and emission maxima at 440 nm and 528 nm, respectively, and demonstrates low cytotoxicity in HepG2 cells at a concentration of 30 μM for up to five hours, making it suitable for various cellular imaging applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
