Product Data Sheet
N-(p-Tosyl)-GPR-pNA acetate
Catalog No. B11117
N-(p-Tosyl)-GPR-pNA acetate is a chromogenic substrate specifically designed for the assessment of synthetic peptides, particularly Hirunorm IV and Hirunorm V. This reagent is utilized to determine the dissociation constants (KI) of these reversible inhibitors of thrombin activity. Through the modulation of peptide concentration, precise evaluation of dissociation constants can be achieved, with values measured at 0.134 nM for Hirunorm IV and 0.245 nM for Hirunorm V, enhancing research in the field of coagulation and fibrinolysis studies.
Chemical Information
| Catalog Num | B11117 |
|---|---|
| M. Wt | 662.71 |
| Formula | C28H38N8O9S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 86890-95-1 |
| Synonyms | Chromozym-TH |
| SMILES | O=C([C@H](CCC1)N1C(CN[S](=O)(C(C=C2)=CC=C2C)=O)=O)N[C@@H](CCCNC(N)=N)C(NC(C=C3)=CC=C3[N](=O)=O)=O.CC(O)=O |
Biological Activity
| Description | N-(p-Tosyl)-GPR-pNA acetate is a chromogenic substrate specifically designed for the assessment of synthetic peptides, particularly Hirunorm IV and Hirunorm V. This reagent is utilized to determine the dissociation constants (KI) of these reversible inhibitors of thrombin activity. Through the modulation of peptide concentration, precise evaluation of dissociation constants can be achieved, with values measured at 0.134 nM for Hirunorm IV and 0.245 nM for Hirunorm V, enhancing research in the field of coagulation and fibrinolysis studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
