Product Data Sheet
HKSOX-1
Catalog No. B11259
HKSOX-1 is a fluorescent dye specifically designed for the sensitive and selective detection of superoxide anion radicals (O2•−) within cellular environments. Utilizing an aryl trifluoromethanesulfonate moiety, this probe undergoes O2•−-mediated cleavage, resulting in the release of a free phenol and subsequent fluorescence emission. HKSOX-1 exhibits high specificity and sensitivity across various pH levels and is resistant to interference from common oxidants and reductants in biological systems. Its derivative, HKSOX-1r, is optimized for cellular retention and has been effectively utilized in assays such as confocal microscopy, flow cytometry, and zebrafish embryo research, making it valuable for studies related to O2•− in inflammation and mitochondrial stress.
Chemical Information
| Catalog Num | B11259 |
|---|---|
| M. Wt | 712.40 |
| Formula | C23H6F10O11S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1786411-17-3 |
| Synonyms | |
| SMILES | O=C(C1=CC=C2C(C(OC23C4=CC(F)=C(C(F)=C4OC5=C(C(OS(=O)(C(F)(F)F)=O)=C(C=C53)F)F)OS(=O)(C(F)(F)F)=O)=O)=C1)O |
Biological Activity
| Description | HKSOX-1 is a fluorescent dye specifically designed for the sensitive and selective detection of superoxide anion radicals (O2•−) within cellular environments. Utilizing an aryl trifluoromethanesulfonate moiety, this probe undergoes O2•−-mediated cleavage, resulting in the release of a free phenol and subsequent fluorescence emission. HKSOX-1 exhibits high specificity and sensitivity across various pH levels and is resistant to interference from common oxidants and reductants in biological systems. Its derivative, HKSOX-1r, is optimized for cellular retention and has been effectively utilized in assays such as confocal microscopy, flow cytometry, and zebrafish embryo research, making it valuable for studies related to O2•− in inflammation and mitochondrial stress. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
