Product Data Sheet
Ursodeoxycholic acid-d4
Catalog No. B11629
Ursodeoxycholic acid-d4 is a deuterium-labeled version of ursodeoxycholic acid, serving as a stable isotope for various biochemical studies. This secondary bile acid, produced by the conversion of (cheno)deoxycholic acid by intestinal microbiota, plays a crucial role in maintaining intestinal barrier integrity and is vital for lipid metabolism. It functions as a signaling molecule by interacting with receptors such as the G-protein coupled bile acid receptor 5 (TGR5) and the farnesoid X receptor (FXR). Ursodeoxycholic acid-d4 is applicable in research focused on hepatic and gastrointestinal diseases, and it demonstrates potential in modulating ACE2 expression, thereby contributing to investigations on SARS-CoV-2 infection.
Chemical Information
| Catalog Num | B11629 |
|---|---|
| M. Wt | 396.60 |
| Formula | C24H36D4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 347841-46-7 |
| Synonyms | Ursodeoxycholate-d4; Ursodiol-d4; UDCA-d4 |
| SMILES | C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@@H]3O)(C([C@H](O)C(C4)([2H])[2H])([2H])[2H])[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H] |
Biological Activity
| Description | Ursodeoxycholic acid-d4 is a deuterium-labeled version of ursodeoxycholic acid, serving as a stable isotope for various biochemical studies. This secondary bile acid, produced by the conversion of (cheno)deoxycholic acid by intestinal microbiota, plays a crucial role in maintaining intestinal barrier integrity and is vital for lipid metabolism. It functions as a signaling molecule by interacting with receptors such as the G-protein coupled bile acid receptor 5 (TGR5) and the farnesoid X receptor (FXR). Ursodeoxycholic acid-d4 is applicable in research focused on hepatic and gastrointestinal diseases, and it demonstrates potential in modulating ACE2 expression, thereby contributing to investigations on SARS-CoV-2 infection. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
