Product Data Sheet
6α-Hydroxy Paclitaxel-d5
Catalog No. B11884
6α-Hydroxy Paclitaxel-d5 is a stable isotope-labeled form of 6α-Hydroxy paclitaxel, a significant metabolite of Paclitaxel (PTX) produced by the liver enzyme CYP2C8. This compound exhibits bone marrow toxicity; however, it has been shown to enhance the cytotoxic effects of paclitaxel against leukemia cells while minimizing cellular toxicity. As such, 6α-Hydroxy paclitaxel-d5 is an important reagent for research in leukemia and related cancer therapies.
Chemical Information
| Catalog Num | B11884 |
|---|---|
| M. Wt | 874.94 |
| Formula | C47H46D5NO15 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1315376-90-9 |
| Synonyms | |
| SMILES | O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)C4=CC=CC=C4)[C@@]5(O)C(C)(C)C([C@@H](OC(C)=O)C(=O)[C@]3(C)[C@@H](O)[C@H](O)[C@]1(OC2)[H])=C(C)[C@@H](OC([C@@H]([C@@H](NC(=O)C6=C(C(=C(C(=C6[2H])[2H])[2H])[2H])[2H])C7=CC=CC=C7)O)=O)C5)[H] |
Biological Activity
| Description | 6α-Hydroxy Paclitaxel-d5 is a stable isotope-labeled form of 6α-Hydroxy paclitaxel, a significant metabolite of Paclitaxel (PTX) produced by the liver enzyme CYP2C8. This compound exhibits bone marrow toxicity; however, it has been shown to enhance the cytotoxic effects of paclitaxel against leukemia cells while minimizing cellular toxicity. As such, 6α-Hydroxy paclitaxel-d5 is an important reagent for research in leukemia and related cancer therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
