1,10-Decanediol-d20
Catalog No. B12712

1,10-Decanediol-d20 is the deuterated version of 1,10-decanediol, a diol compound known for its role in the formation of polymeric microparticles (paKG MPs) upon reaction with α-ketoglutarate (aKG). These microparticles facilitate the sustained release of aKG, promoting immunosuppressive responses by modulating dendritic cell metabolism, including reduced glycolysis and mitochondrial respiration. This modulation impacts the expression of key surface markers such as MHC-II and CD86 and influences the frequency of regulatory T cells and T-helper subsets in vitro. 1,10-Decanediol-d20 serves as a critical tool in immunometabolism research and is also useful as a surfactant or stabilizer in nanomaterial synthesis.
Chemical Information
| Catalog Num | B12712 |
|---|---|
| M. Wt | 194.40 |
| Formula | C10H2D20O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 347841-78-5 |
| Synonyms | |
| SMILES | OC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])O |
Biological Activity
| Description | 1,10-Decanediol-d20 is the deuterated version of 1,10-decanediol, a diol compound known for its role in the formation of polymeric microparticles (paKG MPs) upon reaction with α-ketoglutarate (aKG). These microparticles facilitate the sustained release of aKG, promoting immunosuppressive responses by modulating dendritic cell metabolism, including reduced glycolysis and mitochondrial respiration. This modulation impacts the expression of key surface markers such as MHC-II and CD86 and influences the frequency of regulatory T cells and T-helper subsets in vitro. 1,10-Decanediol-d20 serves as a critical tool in immunometabolism research and is also useful as a surfactant or stabilizer in nanomaterial synthesis. |
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RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


