Product Data Sheet
N-Desalkylflurazepam-d4
Catalog No. B13535
N-Desalkylflurazepam-d4 is a deuterated analog of N-Desalkylflurazepam, a long-acting metabolite of benzodiazepine compounds, including Flurazepam. This stable isotope is primarily used for research applications involving metabolic studies and pharmacokinetics of benzodiazepines. N-Desalkylflurazepam exhibits inhibitory effects on L-type voltage-gated calcium channels, with reported IC50 values of 55 μM for Cav1.2 and 37 μM for Cav1.3, making it a valuable tool for investigating calcium channel modulation in various biological contexts.
Chemical Information
| Catalog Num | B13535 |
|---|---|
| M. Wt | 292.73 |
| Formula | C15H6D4ClFN2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1286430-01-0 |
| Synonyms | |
| SMILES | ClC(C=C1C(C2=C(C([2H])=C([2H])C([2H])=C2[2H])F)=NC3)=CC=C1NC3=O |
Biological Activity
| Description | N-Desalkylflurazepam-d4 is a deuterated analog of N-Desalkylflurazepam, a long-acting metabolite of benzodiazepine compounds, including Flurazepam. This stable isotope is primarily used for research applications involving metabolic studies and pharmacokinetics of benzodiazepines. N-Desalkylflurazepam exhibits inhibitory effects on L-type voltage-gated calcium channels, with reported IC50 values of 55 μM for Cav1.2 and 37 μM for Cav1.3, making it a valuable tool for investigating calcium channel modulation in various biological contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
