Product Data Sheet

Voxelotor-d6

Catalog No. B14964

main product photo
Voxelotor-d6 is a deuterium-labeled derivative of Voxelotor, serving as a stable isotope for research applications. Voxelotor acts as a potent inhibitor of hemoglobin S (HbS) polymerization, making it a promising therapeutic candidate for the treatment of sickle cell disease (SCD). This isotopically labeled compound is valuable for studies focused on pharmacokinetics, metabolism, and the mechanism of action of Voxelotor in SCD.
Chemical Information
Catalog NumB14964
M. Wt343.41
FormulaC19H13D6N3O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2170187-39-8
SynonymsGBT 440-d6
SMILESO=CC(C(O)=CC=C1)=C1OCC2=C(C3=CC=NN3C(C([2H])([2H])[2H])C([2H])([2H])[2H])N=CC=C2
Biological Activity
DescriptionVoxelotor-d6 is a deuterium-labeled derivative of Voxelotor, serving as a stable isotope for research applications. Voxelotor acts as a potent inhibitor of hemoglobin S (HbS) polymerization, making it a promising therapeutic candidate for the treatment of sickle cell disease (SCD). This isotopically labeled compound is valuable for studies focused on pharmacokinetics, metabolism, and the mechanism of action of Voxelotor in SCD.
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