Product Data Sheet

Lofepramine-d3

Catalog No. B15111

main product photo
Lofepramine-d3 is a deuterium-labeled form of the tricyclic antidepressant Lofepramine. Its mechanism primarily involves the inhibition of noradrenergic and serotonergic neurotransmission, contributing to its potent antidepressant and anxiolytic effects. This stable isotope is valuable for metabolic studies and pharmacokinetic research, providing insights into the metabolism of Lofepramine to its active metabolite, Desipramine.
Chemical Information
Catalog NumB15111
M. Wt421.98
FormulaC26H24D3ClN2O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1185083-78-6
Synonyms
SMILESC(CCN(CC(=O)C1=CC=C(Cl)C=C1)C([2H])([2H])[2H])N2C=3C(CCC=4C2=CC=CC4)=CC=CC3
Biological Activity
DescriptionLofepramine-d3 is a deuterium-labeled form of the tricyclic antidepressant Lofepramine. Its mechanism primarily involves the inhibition of noradrenergic and serotonergic neurotransmission, contributing to its potent antidepressant and anxiolytic effects. This stable isotope is valuable for metabolic studies and pharmacokinetic research, providing insights into the metabolism of Lofepramine to its active metabolite, Desipramine.
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SHIPPING AND STORAGE
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