Product Data Sheet

2'-Deoxyadenosine-13C5 monohydrate

Catalog No. B15761

main product photo
2'-Deoxyadenosine-13C5 monohydrate is a stable isotope-labeled analog of 2'-deoxyadenosine, primarily targeting cellular pathways involved in insulin regulation. This compound inhibits glucose-stimulated insulin release and reduces islet cyclic AMP (cAMP) accumulation. Additionally, it activates caspase-3, promoting apoptotic processes, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity. 2'-Deoxyadenosine has demonstrated cytotoxic effects on various cancer cell lines, including those associated with colon cancer, making it a valuable tool for research in cancer biology and metabolic regulation.
Chemical Information
Catalog NumB15761
M. Wt274.22
FormulaC513C5H15N5O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.478510-79-1
Synonyms
SMILESNC1=NC=NC2=C1N=CN2[13C@H]3[13CH2][13C@H](O)[13C@@H]([13CH2]O)O3.O
Biological Activity
Description2'-Deoxyadenosine-13C5 monohydrate is a stable isotope-labeled analog of 2'-deoxyadenosine, primarily targeting cellular pathways involved in insulin regulation. This compound inhibits glucose-stimulated insulin release and reduces islet cyclic AMP (cAMP) accumulation. Additionally, it activates caspase-3, promoting apoptotic processes, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity. 2'-Deoxyadenosine has demonstrated cytotoxic effects on various cancer cell lines, including those associated with colon cancer, making it a valuable tool for research in cancer biology and metabolic regulation.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.