Product Data Sheet
Ganglioside GM2-d3 ammonium
Catalog No. B15787
Ganglioside GM2-d3 ammonium is a deuterium-labeled version of the sialylated glycosphingolipid Ganglioside GM2. This compound primarily targets the integrin β1 receptor, enhancing tumor cell migration and invasion through the activation of the FAK/Src/Erk-MAPK signaling pathway, which induces actin cytoskeleton remodeling. Due to its significant role as a human tumor antigen found in tumor cells and fetal brain tissue, Ganglioside GM2-d3 is valuable for research applications focused on cancer biology and neurodegenerative disorders, allowing for the study of pathological processes associated with its abnormal expression and accumulation.
Chemical Information
| Catalog Num | B15787 |
|---|---|
| M. Wt | 1404.73 |
| Formula | C67H121D3N4O26 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2692623-87-1 |
| Synonyms | |
| SMILES | OC([C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)O[C@H]2[C@H]([C@H](O[C@H]([C@@H]2O)O[C@@H]3[C@H](O[C@H]([C@@H]([C@H]3O)O)OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCCCC([2H])([2H])[2H])=O)CO)CO)O[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O)NC(C)=O)=O.N |
Biological Activity
| Description | Ganglioside GM2-d3 ammonium is a deuterium-labeled version of the sialylated glycosphingolipid Ganglioside GM2. This compound primarily targets the integrin β1 receptor, enhancing tumor cell migration and invasion through the activation of the FAK/Src/Erk-MAPK signaling pathway, which induces actin cytoskeleton remodeling. Due to its significant role as a human tumor antigen found in tumor cells and fetal brain tissue, Ganglioside GM2-d3 is valuable for research applications focused on cancer biology and neurodegenerative disorders, allowing for the study of pathological processes associated with its abnormal expression and accumulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
