Angustine
Catalog No. B18537

Angustine is a monoterpene indole alkaloid that functions primarily as a vasodilator. It demonstrates significant vasodilatory activity, achieving over 90% vasodilation in isolated rat aorta at a concentration of 10 μM. This compound is suitable for investigating conditions such as hypertension, cerebral vasospasm, and peripheral circulatory disorders. Angustine is naturally derived from the bark of Nauclea officinalis and is also found in several other plant genera, including Mitragyna, Uncaria, and Strychnos.
Chemical Information
| Catalog Num | B18537 |
|---|---|
| M. Wt | 313.35 |
| Formula | C20H15N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 40041-96-1 |
| Synonyms | |
| SMILES | O=C1C2=C(C=C3C4=C(CCN13)C5=C(C=CC=C5)N4)C(C=C)=CN=C2 |
Biological Activity
| Description | Angustine is a monoterpene indole alkaloid that functions primarily as a vasodilator. It demonstrates significant vasodilatory activity, achieving over 90% vasodilation in isolated rat aorta at a concentration of 10 μM. This compound is suitable for investigating conditions such as hypertension, cerebral vasospasm, and peripheral circulatory disorders. Angustine is naturally derived from the bark of Nauclea officinalis and is also found in several other plant genera, including Mitragyna, Uncaria, and Strychnos. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
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Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


